I was neutral on it until I talked to one of the Core devs about it. I don't understand all the technical explanation, but I'm now firmly against it. I hope Segwit2x fails.

With 2x, the worst case size is ~8 MB. We don't know how such large blocks will effect the network. It could increase orphan rates, it could cause many nodes to drop off of the network because they can't handle the additional load. We don't know if the network can handle such larger blocks. Just because your internet connection can and your machine can handle the load does not mean that everyone around the world who is running the node can. They may be restricted by things like the Great Firewall of China which may find larger blocks easier to spot and thus make Bitcoin easier for them to block entirely.