First, I personally would never run "Bitcoin safe" with 25k Bitcoins on a Windows computer.
Too big a security risk.

Second, even on Linux, to keep large amount of coins on your computer, it should be extra protected with some complex security.
A virtual machine with Linux on truecrypt-encrypted hard drive with Bitcoin installed should be enough - it will make life much harder for any keyloggers & hackers to infiltrate it.

With computers it is quite easy to do virtually infinately complex system of safes to store your Bitcoins.
You can create a virtual "room of mirrors" using VM in Truecrypt in VM in VM in Truecrypt in VM in Truecrypt and such.

Such an installation could look like this:
Truecrypt(VirtualBox(VirtualBox(Truecrypt(VirtualBox(Truecrypt(Your Bitcoins))))))

You can store some Bitcoins on every layer of this onion, but you should only store large sums on the last layer.