Just have to set some stages to take some profit.  Set a percentage. for every 10% increase, sell 3% of your holdings.  If you keep it at a low percentage, you will always hold a significant chunk even if the price goes way up.

If you want to spend some more energy, you can do a little bit of long term trading this way. Split the takings into profit and then a "short/re-invest" pool.  When the price goes down put some of that money back into the same project  or if you find a new project you want to invest in, put it in that (but save it for an overall bear market).

this way your exit strategy is built in, automatic, you don't have to wonder if you are doing the right thing.