OS X 10.8.3 - upgrade from 0.8.2rc1
Launch attempt #1 - splash screen abruptly disappeared during "Verifying blocks..." and process became unresponsive. Killed the process and tried again.
attempt #2 - Application loaded without any issue.
I will try to replicate the result from Attempt #1 and provide some debug output if possible. Not ruling out it was a problem with the OS itself.