Yes, of course, losing coins or having other significant support non-responsiveness issues could cause a considerable degree of frustration and maybe even loss of money (at least opportunity costs, in the case of dealing with money)....
So, if you are so down and out about Poloniex and you are lessening your exposure, where would you go, instead, to trade Monero and/or ETC?
I'm moving my trading over to Bittrex. They verify accounts quickly, and you get a generous withdrawal limit there based on BTC (Polo's limits are based on USD which increasingly sucks - it's only $2K for a basic account).
O.k.... I am going to look into Bittrex, and it does look like they have a lot of trading pairs, too... so it may be suitable for me, at least in the short term and figure out whether it becomes a comfortable place for a longer duration.