I very much doubt it - no exchanges are particularly transparent on how they operate due to general security related paranoia. Some exchanges may be cloud based, but I think Bitrex may be the only exchange on Azure as (and I'm sure my knowledge is  probably out of date at this point) Bitrex and Cryptopia are the only exchanges that have Microsoft based stacks; where Bitrix is cloud based and Cryptopia is on centralized hardware.

The two differing approaches on hardware is likely due to differing approaches on how the exchanges process the trades. Cryptopia's trade engine is atomic, where every trade is queued and processed in sequence which is a workload suited to a single threaded application; this approach won't work well on the cloud so we can assume that Bitrex does it differently.