Its theoretically possible, but very difficult especially considering the tremendous run that cryptos have had in 2017 from $18B to $170B in market cap. . A more realistic expectation is that you would earn 5 to 15x your capital on your lowest market cap speculative names, but there is also a likelihood that you lose 80% to 90% on these name. My experience is that you can earn these 5x to 15x returns but you need to be a nimble trader, both taking advantage of order book inefficiencies and have insight into the theme that the herd is excited about: masternode coins, privacy coins, smart contract coins, etc. The themes rotate as investors become enamored with various themes at different times. Recently investors have been obsessed with airdrop coins and BTC.

If you want a few low market cap coins to consider with appreciation potetial, here are some: 808, Acoin, Droxne, Prototanium, Sumokoin, Triangles, But I stress these are all deeply speculative coins and I would not put any real capital into these bets.