In the meanwhile I already started re-downloading the blockchain. The question was more like if this is a one-off issue. Frankly, it's a bit of a pain to download the whole thing again after a wallet upgrade.
Thanks.
It shouldn't happen repeatedly.
Although I thought you said it gave that error every time you wanted to reindex, I .must have got confused somewhere.
A copy of the debug log would be helpful examining the issue still though.
Edit: ah I reread the OP. See if the reindexing issue finishes fine and if it reindexes with that error again, it might be a hard drive issue.