Try merged mining in a pool. Same as gpu/fpga mining, only faster
That's a thought, but there isn't one merge mined coin that would be worth it. http://dustcoin.com/mining
The big one everyone will be merge mining with will be NMC. The already low price of NMC will plummet once all the new asic miners decide to sell off all their newly merge mined NMC to help recover their ROI.