For now I can say that FCU + 17.10.3 seems to work well compared to all drivers tested previously.
Unfortunately for me OC with claymore does not work: win 10 bluescreen, video TDR error.
I have to use OverdriveNTool for my MSI 580 gaming X and wattman for my ASUS R9 280x on same rig.
Are you using v10 or v10.1?
I'm using the former and it is working flawlessly on 8 of my Nitros.
is the fan control working for you. I use the same combination FCU + 17.10.3 + v10.0 and one of my cards the fan just starts and stops randomly even though I set the minimal speed to be 1000 rpm in wattman. Another problem is the fan and temp settings in wattman would reset to default values if I restart the rig. It is weird because only one out of six cards showed the fan start/stop symptom.