Plug in 333 Mh/s for $250 into any of the calculators that take into account an exponential rise in difficulty and you will find that these never break even. If the difficulty is rising exponentially, which there are strong indications that it is, these items will make less and less at a rate that means they never pay for themselves at any power use or electricity cost.
I plan on running some and selling some on Ebay. Profits from Ebay means I won't need to cover the cost of the ones that I do run.
Assuming the price of bitcoin will remain the same... - if, in a years time from now 1 BTC = $500 dollars then these little usb gizmos will have been a steel...