Gambling cannot turn into profitable activity if you don't own a casino,gambling site or gambling place. If you are just a regular gambler its not possible because Im sure all your winnings will be use to gamble even more there will be no profits left if that the case.
For majority of gamblers it's not possible because we know that casinos are operating solely for profit so the edge is always on them.
However, there are smart people who can play a luck based games and can be successful in the long run, and also if we believe that casinos always win then we should invest in casino's bankroll, there are a lot of sites that offers this kind of program.