neoscrypt is the best right now. but personally I use automated system that checks diff and profit ratio and point my miners to the most profitable altcoin. I get very good results with this strategy.
Are you using one of the known multi miners? If so, which one? I have been thinking about going this route but not looking forward to the down time setting up and testing the various ones.
I user hashrefinery and pointed it at Skein only. At 75% TDP I'm getting about 60,000-80,000 satoshi / day