Well, Binance seems to be a good exchange and many would like to trade there. I have done some small trading but its a pain without automation, you have to be all over it.
Plus, it doesn't really matter how many markets they currently support, for all I know they could be supporting 1,000 markets in six months. What are we going to do then?

I would suggest to talk with them and explain the problem. We dont want an application cluttering with thousands of API calls - and I'm pretty sure they don't want this as well.