People that used Bitcoin to buy drugs most feel terrible thinking about all that cash they could of had.
So what you are saying? Back then no one thought that the Bitcoin prices would increase by 1,000x. That's how one of the users (Laszlo Hanyecz) purchased a pizza spending
BTC10,000 ($80 million in today's exchange rate). You can still find the pizza thread here:
https://bitcointalk.org/index.php?topic=137.0Laszlo is still active, although he doesn't post much these days.
Good that i saw this post, because my first impression was that this thread is about drugs like marijuana etc

Laszlo is a legend! I'm not sure if it was his billboard, because he payd 10k BTC and on this billboard is 5k BTC.
People on this forum confirm that was real and was somewhere in Los Angeles:

Chemical compounds are very dangerous, so I always advise against buying any medicines/drugs over the internet unless they are natural.
But if you're talking about paying for drugs in "on ground" pharmacies, that's a great idea! Bitcoin adaptation in every industry is another step forward and development.