Thank you all for the suggestions. I did verify under "Ports" in device manager that they are listed at COM5 and COM7. I am still using the USB to UART drivers with 3.1.1, will give a shot at WinUSB drivers with 3.2.2.
No hub is being used, I tried the ports in the front of the desktop as well as the ports in the back of the computer, directly on the motherboard. No hub is being used. I will do more troubleshooting and report back with my results.