I had 2FA on Poloniex. Couple days ago I changed smartphone, setup 2FA with recovery code but Poloniex does not accept codes anymore :-(. Sent a ticket to support 2 days ago. Just silence no reaction.
Should I consider that I lose deposit?
Poloniex has a massive backlog for tickets - it might take a few weeks for them to respond.
You can try making a reddit account and then sending a private message to
https://www.reddit.com/user/Mike-Poloniex and send him a private message with your ticket number.