I have a friend who have the exact motherboard you are asking and he is running 6x RX 580 with modified bios making 180 Mhash in Ethereum only mining mode , running from a few months without problems and without crashing.

It should work for you too but I suggest to go for Biostar TB250 PRO BTC or ASROCK H110 PRO BTC+ or ASUS MINING EXPERT as these are motherboards dedicated to mining. Their price is not expensive too.