It's not going to affect the BTCUSD market. The price continues to push new all-time highs as we speak, hours after the news dropped. The losses are estimated at ~$60 million, which is paltry compared to the overall market.

However, I will say that NiceHash was the most reputable cloud mining service. I know a couple altcoin miners that regular rent hash rate from them, and I'm guessing they were affected by this. It will definitely send some shockwaves through altcoin and miner communities, and it will probably have some effect on POW altcoin hash rates.

I'm skeptical about the circumstances. It sounds like they kept their bitcoin holdings all online on a live server. That's violating security 101 for an operation as large as NiceHash. It starts to smell like an exit scam....