I've never had those kinds of issues you're describing. The Bitcoin Wallet chrome app contains most of the altcoin wallets. To use Litecoin and most of the other altcoins (not Ethereum), you open the Bitcoin chrome app and the correct altcoin app on your ledger. So your steps would be to open the ledger Bitcoin chrome app, connect your nano s, unlock it, and open the litecoin app on your nano s. The window should then load on your computer and display the litecoin wallet.