I'd of course be interested to see if anyone has tried them. Everything I've read doesn't seem to indicate much change for Vega

https://www.anandtech.com/show/12147/amd-releases-radeon-software-adrenalin-edition

"So in short, Adrenalin details nothing Vega-specific and there was no information disclosed on what Vega optimizations are coming when. The focus is on interaction and availability of the features within."

http://www.tomshardware.com/reviews/radeon-software-adrenalin-edition,5384.html

"Vega owners won't see the Graphics/Compute switch in AMD's driver. According to company representatives, all of the features that benefit compute workloads are already enabled by default in Vega's architecture, so the switch isn't necessary."