The biggest pain seems to be now browsing .bit domains.
Already posted this in
the other namecoin thread, but I should mention it here, too:
Windows 7:
Control Panel > Network and Internet > Network and Sharing > Connections: Local Area Connection > Properties > IPv4 > Properties > Use the following DNS server > 178.32.31.41
Windows XP:
right-click the mini icon of your active network connection, then select Status > Properties > TCP/IP > Properties > Use the following DNS server > 178.32.31.41
Mac OS:
System Preferences > Network > Advanced > DNS > DNS Servers: + > 178.32.31.41
(You need an unrestricted user account, of course).
Then open any standard browser and first try one of the following:
http://dns.bit/http://nx.bit/http://bitse.bit/