Hi there,
1st of Good luck and God Speed.
Then buy 2 or 3 Hardware wallets and make sure you safe guard your investments. (Ledger Nano S &/ Trezor)

My suggestions (or My investments if I had that much would be...)

Buy 1 BTC and HODL, like forever..
Buy 25 ETH and HODL, like forever..

now ~40K $ invested, lets go for Alt coins. Includes both short term & Long term.
Sell 50% when each one turns 2x, so that your investment is returned and what ever you HODL will be your profits

Ripple - 5k $
IOTA - 5k $
XPSEC - 5K $
PASC - 5k $
Verge - 5K $
NAV coin - 5K $
DigiBytes - 5K $
BURST - 5K $
Po.ET - 5k $
RaiBlocks - 5K $
Dent - 5K $
FunFair - 5k $

Research well & choose what you like and increase / decrease amount as you fit.

Also try to keep a watch for a good ICO.