As far as i know, only etherdelta is the most safest of all exchange, but i suggest you to save and put your money in a wallet so that it will be kept because you cannot rely on any exchange in keeping your coins.
If you are holding many btc or just invested and do not want to sell it for long term than you should ideally be saving it offline. But if you want to do trading or buy/sell for a short term and do not have much value worth than you can safely keep it in binance or other good exchanges.