A bit late here, but I thought I would give my thoughts on this.

First of all you should only ever invest what you are willing to lose, in this volatile market your portfolio can go up by 50% one day and back down by same amount the next.

You have to realize that this can happen. Best is to just hold coins, and only look at your portfolio every once in a while. incremental losses way more heavily on the mind than incremental gains.

Set targets for coins, set alerts, and exit when you are comfortable with your gains.

Also to avoid losing money, don't margin trade, that can go horribly wrong.