Regarding the PASL profits:
Currently there is an Pascal ASIC thats finished production and there are thousands of GPUs which are dual-mining this coin. Hence its not wise profitability wise to solo or single mine this coin on GPUs such as the 1080Ti. Please only dual mine this coin along with some other Ethash type coin.
Any chance to prevent this ASIC from mining?
Probably the only way to do so would be to combine pascal algo with another or fork to something else. Look it up. Its basically a mini dedicated computer. Don't worry - GPU miners will always find a way.
Its actually an interesting project. It can mine all the current GPU algos. Even ethash.