One of my friends is getting his hands on a 19-slot mobo... Funny thing is he has no idea how to set up the damn thing.
What's the latest on Windows' support for more than 8 GPUs of the same brand? Would I have to set him up a Linux distro if he wanted to run 19 GPUs on that mobo? Or is 16 doable under Win10? I wasn't recommending that mobo to him due to the major point of failure risk... but hey ho he went for it. Now I can see myself setting it up for him...

That board needs 6 x P106 Mining card, as pre-req to work.
See full rig setup by BBT here -
https://www.youtube.com/watch?v=miUoqnUqk9MHe did it with Win10 - 19 x GPUs
Does it NEED those P106's though? Can it run 16 cards (8 nvidia and 8 AMD)?
If I remember correctly BBT started with p106's and started adding normal GPU's to max it out instead of the other way around. I would check the latest BIOS/chipset drivers for updates on compatibilty, but 8 normal Nvidia and 8 amd should work fine, or start with 13 AMD and add Nvidia one at a time. The worst part of that board is the crazy loading times and then trying to load OC values after that. Seems more feasible to stick with 8-13 GPU motherboards.
I agree, and that's what I told him. Easier to manage 2-3 smaller mobos than this juggernaught which will probably end up being a massive pain in the ass.
Everyone's jumping onto the mining bandwagon nowadays. Got colleagues at work flocking to me as they hear I'm into crypto. Helped one of them ordering parts. My plumber/electrician has setup a rig and I was walking him through how to get his mined coins out of Suprnova into his Coinomi wallet!

I have 7 of these 12/13 GPU rigs in the farm and .... yes it is fun building these rigs but you need plenty of power for them and well ventilated. All of them are with the Deltas 2400w and housed in the center of the farm so that I can use the air extractor on them during the hot days. These rigs are the hottest in terms of temps and hash power. Ironically these rigs are the only ones that are hanging like bats and since they are stable, they will likely remain with risers. Multiple 8 x GPU riserless rigs are ideal for density and can fully populate open cage metal racks and make use the of floor fans effectively. I dont forsee doing anymore AMD rigs (exception of the Vega rigs) because the NVIDIAs are a blessing - always works, easy to control voltage and very stable in most cases.
So lessons learnt - the bigger the rigs, the bigger the issues in PSU requirements, cooling strategy, cabling, stabilizing them.... a golden rule : stability, cool temps and consistent submission of shares to the pool's stratum server are more important than achieving the meanest powerful, fastest rigs that requires constant babysitting. If you have a large farm -- undervolting is very very key - forget the world GPU speed record.