That is quite a lot of money, so it is probably best to put the majority in safe picks, such as ETH, NEO, Qtum. Then pick some established coins with room to grow (SUB, VEN, WTC, QSP, REQ, XBY..). And maybe also consider an ICO for excitement, but make sure to do your own research first. To me, this one looks very promising and is highly rated by ico rating websites too:https://www.hoqu.io/?ref_id=0c1d51f3465bda51aac7f3016f84a20e