As always investing in very new companys is risky! But with risk comes reward!
When investing in an ICO, always do your own due dilligence. Start of by reading the whitepaper of an ICO and determine if the problem is indeed to be solved. Then look at the reputation of the team (members). Than decide if you want to HODL for long term result (note: alot of startups dont make it to finished product), or you want to flip them for quick profits (selling on exchange after crowdsale).
It's a shame that Nucleus Vision has already closed it's whitelist. I really would like to be invested in them, they look like the safe and sure option. For now all I can do is support them with my signature

You can buy their tokens once they are sold through exchanges.
Bluzelle is also getting hyped! Gems is a upcomming ICO where you can still apply for whitelist.