Overcool,
All I can say is you rock sir! I switched to Nanopool two weeks ago from Dwarf and have been killing it.
I have 2x GX 1060 6GB cards hitting at 24MH/s each, and 2x RX 580 8GB cards hammering away at 31MH/s each. After finding the sweet spot for OC setting on my 1060s, and doing a vbios flash for the 580s I get the hash rates. I'm working now to find just how low undervolt I can get to reduce power draw at the socket. Currently my rig pulls 740 watts steady (using Kill-A-Watt meter).
My only question is about the default time set for restarting the miner when no share has been submitted in the last x minutes. I believe its 45min? I've only seen this a hand full of times, but wondered if there a way to reduce that time?
Lastly, I'd second Fuitmint's comments....if you get some time, a dual-mining option would put a cherry on top

-Taterbum