I just switched to the dstm client and having zero issues with my 1080ti.  Actually Its OCed more and clocked higher than I have ever been before!  
Before using a different miner (EWBF) I managed around 700 H/sec with just a +100 on the core.  No benefit to clocking the memory or anything else higher.  Now I can run +200 Core / +500 Mem and even run at 90% TDP and get 752 H/sec!  If I run at 100% TDP I get around 770 H/sec at these settings.  I have yet to test it further but I'm sure I could tweak it even more.  So I'd say with this at v0.5.8 you can mine at higher speeds and better output.