I know a lot of people whose doing well in business eventhough they lack in education. But when i ask some of them, they said that if they got a chance to go to school they would,  coz i it would be of great help to them.
Most of these businessmen i know have guts and a  positive attitude. They value every penny, every effort   whether they lose or gain or small or big. The important is the experience and knowledge they pick along the way. And they use  these tools to their everyday business. And another thing is that you love what you do and care for people.