Absolutely. There are a number of ways to do this, nearly all of which are to a certain degree convoluted.
Personally I prefer to transfer them to a debit card and then I can use that to spend or withdraw as normal.
There are a bunch of bitcoin debit cards around and they all serve much the same function but remember you are still paying with a Fiat Currency such as EUR, GBP or USD.
There are a number of prepaid debit cards that can receive bitcoin as a top-up method but they are converted to the Fiat currency for use with the card.