You're limited by the minimum trade amount of the exchange. Whatever Binance's minimum is, that's your minimum. Any less, and the trade won't execute.
Config pools are used to override your default settings for individual coins. For instance, if you know a coin is going to moon, or might crash, you can use config pools to have specific settings for that one coin. If you don't use config pools, then every coin will trade based on your default settings.
I personally don't have config pools on my coins. i will be using them when i learn that a coin is about to take off, so I can keep it from taking 4-6% profit on the coin and miss out on the big runs. That requires regular adjustment and allows me to use my charting skills to make a bigger profit, however at this point I'm pretty hands off with this bot.
In this down market, i've been setting a 15-20% stop loss on my coins. I've found some calls ended up losing 40-60% and i found myself stuck with a bunch of coins that i'm now waiting for to recover.