By far the easiest step by step guide to setting up Claymore can be found here http://www.cryptobadger.com/build-your-own-ethereum-mining-rig/ It talks about RX570's but getting Claymore setup with a mining pool is the same no matter what card you use. There is also a lot of general information on that blog explained well.

Once you are confident that your are setup, and understand the basics then I would recommend you look at undervolting and overclocking http://jkcrypto.com/mining-overclock-settings-for-nvidia-cards/

Also buy a decent electricity usage monitor like Kill-a-Watt https://www.youtube.com/watch?v=9fkYTp_gETU so you know how much electricity you are using.

Lastly it should be fun, I've built 3 mining rigs and enjoy building them, but there is a bit of a learning curve so it's better if you enjoy what your doing! Good luck with it