As a relative newbie to the code, I do find your version easier to read. It's easier to find the implementations of functions since most are class members and are now in named .cpp files. It's also nice to have the full class implementation in one place rather than having to flip back and forth between .h and .cpp files.

However that is for reading, and the needs of developers may be somewhat different. Obviously Satoshi knows the current layout intimately, and as the main developer it is up to him to see whether he could work with the new layout.

One concern I'd have with losing the inlinable .h functions is whether it could slow down either initial block load/verify/indexing, or mining (a bit moot with gpu miners these days).