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I started off with 2 x 2 pacs which I had no problem with. So bought a few more from eyeboot.com along with USB hub
The more miners I put into the USB hub the worse the performance of the miners.
I'm running win10 ...
I slightly recall someone having that issue before and overcame it by starting up separate instances of cgminer.exe.
Possibly a cgminer+windows quirk.
First, grab the latest build of cgminer from the first post (Feb 10, 2018 @ 4a3f595).
Then start up with the extra parameter "--usb :2"
Slowly increase that 2 up until performance start decreasing then run cgminer.exe in another window, same parameters.