if you want to exchange your coin in money directly after the payout, you should aim for the most profitable coin (and probably change every day). If you want to hold, then you should select a coin that has the highest chance of survival because there are already too many different coins on the market and many of them will fail sooner or later (if not all of them at some point). I believe coins like ETH have this longer term potential.

What I also did is investing a low amount of money every month buying some low value coins knowing that they may disappear but if one of them hits the roof, you easily get the money back. I bought XRP when it was below 1$, went up to almost 3$, good deal. With the benefits I bought other coins of a lower value.