It is not so much difference between genial and crazy.

This is a legitimate question because virtual life will differ from real life.
The scan of the cerebral cortex will be the main part of the uploaded mind. The brain centers for seeing and hearing will not be implemented but there will be standard modules to attach a webcam.
So disabled persons which have motor disabilities or disabilities in their audio-visual input will not be in disadvantage like in real life.
The activation of uploaded persons will need to make a complex check by start to see if they are in the main chain otherwise it will be not possible to avoid duplication.
However it could happen that hackers will crack some older mind backups to run them on their own network and they will work like kind of clones.