Extreme example:
Showing something ugly is not an argument against developing something elegant and beautiful.
There is no argument, just make what you want. If you want a iPhone-like GUI, make a iPhone-like GUI. If you want a better wxWindows-based GUI, make a better wxWindows-based GUI. I really don't understand some of the people here.
You can either work with me or do your own thing. Open source = freedom.