The same goes with mining, it is not profitable anymore for you to mine coins at home, it must be done with ASIC and in a large scale to be profitable over time.
Why has it to be done in large scale to be profitable?
...
1. Mining with the chips you yourself manufacture, thus eliminating marketing & supply chain expenses.
2. Getting electricity at the best available rate -- anywhere.
3. Maintaining 1,000 miners cost less than maintaining (a single miner) * 1000.
4. etc., etc., etc.