I did, never get any issue with that, about performance on my highend stuff is barery feelable, or there is no difference at all.
I once got well paid for sorting out a 2GB MS-Access database with about seventy user and put it on RAM-Disk and this
thing flew after that so maybe if your running a cluster of rigs then this might become an option and I am not talking about
sold state disks here but full on DDR3/5