If desired, you can break 2fa
Indeed, with a good skill of social engineering or a decent amount of drugs to force the victim to give up his phone with the key to unlock it.
It's the first time I hear about drugs being used for that purpose.
Usually you just have to steal a phone or to get access to it programmatically. Or use threats.
Not a lot you know about the real life

A friend of mine works in police, he's told me about this practice. If you want, I can ask him on what drugs are used.