I kind of think these multi-coin pools are a quick way to make the current "most profitable alt-coin" into a pump and dump. It both increases the supply of one/few alt coins simultaneously, which makes selling at market value difficult while it also (to me) devalues alt coins as a whole.
Which is rather unfortunate, I see some virtue in Primecoins and Freicoins for instance, they both offer some cool features and ideas.
That's one way to look at it. But big miners that routinely change allegiances based on market factors (which is all a multipool is) are a commonplace and inevitable aspect of the cryptosphere.
And they cannot change the inherent merits of any particular coin, which is and must always be the primary factor elevating any worthy coin.
So do you deposit directly to Cryptsy then?
It's an option. For non p2pool type pools only.