And how many persons holds those 250 adresses? I would guess very few.
14o7zMMUJkG6De24r3JkJ6USgChq7iWF86 (#6 on the most recent list) is the Just-Dice.com cold wallet. It represents coins belonging to the 730 people who "crowdfund" the site's bankroll. I expect others high on the list are also collectively owned by many people.