The effects of drugs on the body can cause harm to the organ systems and may finally lead to their collapse. Some drugs, like heroin, have to be injected with intravenous needles. Continuous usage of this drug can affect the veins and leads to their collapse. it also triggers infections in the lining of the heart. Sharing of needles can increase the risk of contracting hepatitis and AIDS, which can result in death.
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https://www.buzzle.com/articles/effects-of-drugs-on-the-body.html