Did they have any prior conditions? Did they mix the substances with something else? What exactly did they take?
I'm not talking death of course, they just wound up as vacant shadows. I dunno if there was something underlying in each case, but the eagerness people have to upend their brains is a little befuddling to me. You have no idea what effect they'll have on you yourself until you're too far gone to do anything about it.
The way I see it is, I supposedly only get one life and want to experience as much of it as possible. Of course that demands caution as well, but I've spent roughly a decade researching all sides of the story for every substance that I've ever tried and ultimately concluded that the risk/reward ratio for (some) psychedelics was in the favour of taking them, at least for me. I've made sure that I knew what to expect to the best I could and started small with no obligations for the coming days. At the end of the day, it was like Cannabis turned up to 11.