Same shit happening to me - this is a shame, now I cannot access my funds any more, everything is blocked. This is NOT what one would expect from a product like Nano Ledger.
Did you actually check the device manager if one USB-device has a yellow explaination mark beside it?
If so, you simply need to open the properties and 'install the driver' (windows USB-driver; should be done automatically by windows).
If this is not the case: Are you able to access the ledger manager? Or is your nano s completely stuck?
If you really need to access your funds asap, you can simply import your seed into another wallet (e.g. electrum [1]).
But consider your seed as compromised from this moment on. When moving your funds back to the ledger, you should create a new seed.
[1]
https://electrum.org/#home