Actually it does not matter what amount of money do you have to invest.
First of all you have to minimise your risks, so It is better to divide your portfolio on groups such as:
Bitcoin - 20-30%
ETH,LTC,NEO,Monero, Dash - 20-30%
Iota, EOS, Waves - 10-20%
More risky: TRON, Verge etc. - 10-20%
ICO - 10-20%

Anyway you have to make an analysis of the market in order to pretend on profit.