Well, yes! If it features a good CPU. Let's say high i3 or low i5, 8 GB DDR4 Ram, 512GB and up HDD and an ethernet cable. (Data transmission is much, can't rely on wifi). Run a virtual box software --> Install Ubuntu. Set-up the masternode in your Linux distro. Let masternode update the blockchain and just run it in the background. That's it. Note: Only do it when you're running Windows 10 and you meet all the above requirements. A Virtual box separates the resources that are in need by virtual OS and thus not interfering with mining process in Windows.